Objetivoĭescribir el uso de CNAF en pacientes pediátricos que ingresan con insuficiencia respiratoria y explorar los factores asociados al fracaso de la terapia. No se ha descrito su comportamiento en gran altitud. Las cánulas nasales de alto flujo (CNAF) ofrecen una nueva alternativa, pero sigue existiendo debate en torno a la evidencia e indicaciones. The differences found between institutions suggest a subjective relationship in the decision of therapy failure.Įl fallo respiratorio agudo es la principal causa de hospitalización en pediatría. HFNCs afford good clinical response, with few complications and a low failure rate. The final logistic model established an independent relationship of failure between the hospital (OR 2.78, 95%CI 1.48–5.21) and the initial respiratory rate (OR 1.56, 95%CI 1.21–2.01). Improvement was observed in vital signs and severity over time, with differences in the group that failed, but without interactions. The median length of stay was 4 days (IQR 4) there were 5 deaths (0.9%) and 13 adverse events (epistaxis) (2.2%).
There were 53 failures (9.8%), with 21 occurring in the first 24 h. Infants (70.9%) of male sex (58.4%) and airway diseases such as asthma and bronchiolitis (61.2%) were more frequent. ResultsĪ total of 539 patients were enrolled. Patients with treatment failure were compared with the rest. The number of failures was determined, as well as the length of stay, complications and mortality. The demographic and treatment response data were recorded at baseline and after 1, 6 and 24 h. MethodologyĪ prospective cohort study was carried out in patients between 1 month and 18 years of age managed with HFNCs.
To describe the use of HFNCs in pediatric patients admitted with respiratory failure and explore the factors associated with treatment failure. The performance of HFNCs at high altitude has not been described to date. High-flow nasal cannulas (HFNCs) offer a new alternative, but the evidence and indications are still debated. Acute respiratory failure is the leading cause of hospitalization in pediatrics.
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